For the first time, scientists have performed prenatal gene editing to prevent a lethal metabolic disorder in laboratory animals, offering the potential to treat human congenital diseases before birth. Published Tuesday in Nature Medicine, research from Children’s Hospital of Philadelphia (CHOP) and the Perelman School of Medicine at the University of Pennsylvania, United States (U.S.), offers proof-of-concept for prenatal use of a sophisticated, low-toxicity tool that efficiently edits DNA building blocks in disease-causing genes. Using both CRISPR-Cas9 and base editor 3 (BE3) gene-editing tools, the team reduced cholesterol levels in healthy mice treated in utero by targeting a gene that regulates those levels. They also used prenatal gene editing to improve liver function and prev
The “largest genetic association study of blood pressure traits” to date has studied over one million people and found 535 new genetic loci linked with the condition. This finding may help predict the risk of high blood pressure and identify better treatments. Worldwide, the condition is the leading cause of cardiovascular death. High blood pressure can cause many serious conditions, such as heart attack, stroke, heart failure, kidney failure, and the loss of vision, among several others. Risk factors for high blood pressure are also numerous and can be divided into modifiable and non-modifiable ones.A lack of physical activity, smoking, an unhealthful diet, excessive alcohol intake, stress, and being overweight are some factors that heighten risk but that can be changed or modified. How
Inspire Nurses Network Africa (INNA), an NGO, has said 90 per cent of Nigerian Nurses lacked basic life support skills on emergency care. Josiah Okesola, Leader of the group, disclosed this while fielding questions from the News Agency of Nigeria (NAN). Okesola, who was accompanied by Mrs Regina Askia-Williams, emphasised that every nurse was supposed to be trained on emotional intelligence and critical thinking as well as basic life support skills. She said these would enable them to respond effectively to emergency anywhere they found themselves. NAN reports that emotional intelligence is an important characteristic of nurses that could affect the quality of their work including clinical decision making, critical thinking evidence and knowledge of practice. Basic life supp...
If you frequently experience shortness of breath or you hear a whistling or wheezy sound in your chest when you breathe, you may have asthma. What is Asthma? Asthma is a chronic lung disease that inflames and narrows the airways in the lungs. Asthma attacks all age groups but often starts in childhood. According to WHO estimates, 235 million people suffer from asthma globally. Although asthma cannot be cured, appropriate management can control the disorder and enable people to enjoy good quality of life. People with a family history of allergies or asthma are more prone to developing asthma. In addition, some children with milder forms of asthma outgrow their symptoms with age. If people with asthma are exposed to a substance to which they are sensitive or a situation that change...
War Against Mosquitos: War against Malaria: Finding an Appropriate anti-Malaria Drug is quite a challenge because of the numerous anti-malaria medication and drugs out there, also not being sure about which one actually works even makes it more complicated to choose: one would mostly depend on the recommendations made by their doctor or pharmacist. Victoria H. says: After using a couple of anti malaria Drugs I finally found one which always knocked out malaria quickly John B. says: I find Zeramal better, convenient and affordable because rather than having to take 24 tablets for a complete dosage, Zeramal gives me just 6 for a complete dosage. Its really awesome! We would also want to know which one works best for you and why. Malaria being knocked out by the zeramal Brand A delu
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healthy Lifestyle, a big priority: A healthy lifestyle can help you thrive throughout your life. Making healthy choices isn't always easy, however. It can be hard to find the time and energy to exercise regularly or prepare healthy meals. However, your efforts will pay off in many ways, and for the rest of your life. A healthy lifestyle is a big priority. Guide to living a Healthy Lifestyle: Be physically active for 30 minutes most days of the week. Break this up into three 10-minute sessions when pressed for time. Healthy movement may include walking, sports, dancing, yoga, running or other activities you enjoy. Eat a well-balanced, low-fat diet with lots of fruits, vegetables and whole grains. Choose a diet that's low in saturated fat and cholesterol, and moderate in sugar
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Harmful Substances in Cosmetics: Did you know that over 60% of what you put on your skin, the largest organ on your body gets absorbed into your blood stream? And unlike your kidneys and liver that act as your body’s filter, the skin is all on its own. 95% of the chemicals in most commercial cosmetics and personal care products are made from harmful substances. This is because it appeals more to the eyes of the consumers and also would sell real fast. It is important to check the ingredients listed on cosmetic and personal care products before you buy. Quite a number of the so called ingredients are harmful and may rank among causes of skin cancer and few other health problems. Below are some of the ingredients to watch out for: Parabens: Parabens are synthetic preservatives us
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The Fight Against Counterfeit Drugs: Nafdac The immediate past director-general of National Agency for Food and Drug Administration and Control, Dr. Paul Orhii had prior to his exit from office been widely quoted as advocating for the enactment of new legislation to enable the agency cope with the present realities on the dynamics of war on counterfeit medicines among other challenges confronting it. The former NAFDAC helmsman had hinged his call for a revision of the laws on the noticeable defects in the existing ones to enhance efforts of the agency to rid the country of unscrupulous elements. We support Orhii’s advocacy because it borders on strengthening the operations of an important agency of government whose activities have direct consequence on the lives of the greatest majori
Cardiologist caution Nigerians About what they consume: Cardiologist caution Nigerians About what they consume, Dr. Sabu George is a Nigerian heart expert based in the United States of America; recently he alerted Nigerians on the inherent dangers in the over-indulgence in some popular foods and drinks as consumed by Nigerians. George cautioned that these foods regularly consumed in the country are capable of leading to cardiovascular-related diseases. Eating Healthy Meals: He noted that staples like bread, pounded yam, noodles, cassava as well as soft drinks can endanger your blood pressure and the health of your heart if care is not taken. During a three-day free health screening programme – ‘Medical Mission’, put together by the Apapa-Iganmu Local Council Development Area (LCD
Fake Anti Malaria Durgs-Beware: Following the emergence of two fake versions of Quinine Sulphate circulating in neighbouring Cameroon and the Democratic Republic of Congo, the federal government has recently warned Nigerians to beware. According to official reports, the fake drugs contain zero active pharmaceutical ingredients. The report states that however, the said drugs have not been sighted in the country yet, but if seen anywhere including hospitals and pharmacy shops, it should be reported to the nearest office of the National Agency for Food and Drug Administration and Control (NAFDAC). Warning : The warning which was contained in a statement released by Mrs. Boade Akinola, Director of Press and Public Relations, Federal Ministry of Health, also revealed that Quinine Sulpha
NEW INSIGHTS TO THE IMPORTANCE OF A HEALTHY BREAKFAST: Eating breakfast isn't just for kids. Although you've probably stopped growing, your body is constantly renewing itself, replenishing your skin, hair and nails, replacing old tissues with new, breaking down and rebuilding bone and generally keeping your body in the best shape possible. Breakfast is a critical meal because it influences practically every dimension of our being during the course of the day, including how we perform physically and mentally. Breakfast immediately raises the body’s energy level and restores the blood glucose level to normal after an overnight fast. READ MORE Breakfast-skipping is linked with being overweight: Although a direct effect of skipping breakfast on weight has ye
One would tend to ask, how possible is it for a child to survive outside the womb, or could it ever be possible that a child be born out of a plastic in place of a woman’s womb? Yes! And it’s called ectogenesis, a term coined by British scientist J.B.S. Haldane in 1924 which means - raising a foetus outside the human body in an artificial womb. He predicted that by 2074 only 30 percent of births would be human births. Science has grown much quicker than he realised, and his take is probably much too conservative. Recently, Scientists sustained human embryos in a petri dish for 13 days, shattering the previous record of nine days. The ectogenesis technology itself is highly complicated and would require an artificial uterus. An artificial uterus would have to be supplied by nutrients and
It is no longer news that about five per cent of the world population are suffering from one form of hearing disability or the other,. representing about 360 million people across the globe, according to the World Health Organisation (WHO). What seems to be the news is that this number is predicted to increase in the coming years, especially in low and middle income countries like Nigeria where there are no significant approaches and will power to tackle the scourge. Recently, according to the Chief Executive Officer of International Centre for the Preven-tion of Deafness and Rehabilitation of Hearing Impaired Persons (ICPDRHIP), Dr. Audu Eneche, about 6.7 per cent of Nigerians were suffering from hearing disability, meaning that of the country's 180 million persons, over 12...
Bada advised people to imbibe the habit of eating healthy and doing more exercises to improve healthy living that would make them live longer. Two medical experts in Lagos advised the general public to observe healthy lifestyle, to reduce the occurrence of sicknesses. Both men expressed the viewpoint in separate interviews with the News Agency of Nigeria (NAN) saying that people must be physically and medically fit to be healthy. Dr Ibrahim Hazoume, a Public Health physician at Green Hill Hospital, Ikorodu, defined healthiness as the absence of disease and good mental status of an individual, while wellness was more of a lifestyle. Hazoume defined being well as "keeping active, eating a balanced diet, getting fit, losing weight, quitting smoking, limiting alcohol, eating fruits and v...
According to the First safety Study of the hallucinogenic approach, hallucination drugs can be derived from a particular type of magical mushrooms which studies suggest could be useful in the treatment of depression in people. Researchers from The Imperial College London gave twelve people psilocybin, an active component in the said magic mushrooms. Those affected had been clinically depressed for a significant period of time on an average of 17.8 years. None of the patients had responded to standard medications such as Selective Serotonin Re-uptake Inhibitors (SSRIs), or had electroconvulsive therapy. One week after receiving an oral dose of psilocybin, all affected or rather depressed patients experienced a marked improvement in their health conditions. After three months, five patient...