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Jaundice revisited: recent advances in the diagnosis and treatment of inherited cholestatic liver diseases

Jaundice revisited: recent advances in the diagnosis and treatment of inherited cholestatic liver diseases

NEWS
Abstract Background Jaundice is a common symptom of inherited or acquired liver diseases or a manifestation of diseases involving red blood cell metabolism. Recent progress has elucidated the molecular mechanisms of bile metabolism, hepatocellular transport, bile ductular development, intestinal bile salt reabsorption, and the regulation of bile acids homeostasis. Main body The major genetic diseases causing jaundice involve disturbances of bile flow. The insufficiency of bile salts in the intestines leads to fat malabsorption and fat-soluble vitamin deficiencies. Accumulation of excessive bile acids and aberrant metabolites results in hepatocellular injury and biliary cirrhosis. Progressive familial intrahepatic cholestasis (PFIC) is the prototype of genetic liver diseases man...
Before testing positive for COVID-19, Kyari mingled with govs, ministers, others

Before testing positive for COVID-19, Kyari mingled with govs, ministers, others

NEWS
President Muhammadu Buhari, Vice President Yemi Osinbajo, many governors, ministers and other top government functionaries mingled with Malam Abba Kyari, the Chief of Staff to the president shortly before he tested positive to the coronavirus (COVID-19). Kyari, who returned to Nigeria from Germany on March 14, had participated in several state functions and unofficial engagements that attracted prominent personalities. It was gathered that yesterday’s confirmation that Kyari tested positive to COVID-19 necessitated the subsequent test on President Muhammadu Buhari, which turned out to be negative. Similarly, Bauchi State Governor, Bala Abdulkadir Mohammed, who also tested positive to the COVID-19, had also visited Germany not long ago and on his return, he had attended many functions in
Coronavirus: All suspected cases in Nigeria tested negative – NCDC

Coronavirus: All suspected cases in Nigeria tested negative – NCDC

NEWS
The Nigeria Centre for Disease Control (NCDC) on Thursday confirmed that all the 31 suspected cases of Coronavirus in Nigeria tested were negative. “This means Nigeria is free of Coronavirus,” the Director, Emergency Preparedness and Response, NCDC, Dr John Oladejo said. He disclosed this in Sokoto at a symposium on “The emerging and re-emerging Viral Infections: The story of Lassa fever and COVID-19,” organised by the Usmanu Danfodiyo University, Sokoto. He assured that the NCDC has the necessary devices to detect the disease adding that screening has been strengthened at points of entry while in-country surveillance has been enhanced through state epidemiologists. On diagnostic capacity, he stated: “We now have testing capacity in three laboratories: National Reference Laboratory, Abuj
Iran reports 144 new coronavirus deaths, raising total to 2,378

Iran reports 144 new coronavirus deaths, raising total to 2,378

NEWS
Iran on Friday announced 144 new deaths from the novel coronavirus, bringing the official number of fatalities to 2,378 in one of the world’s worst-hit countries. “In the past 24 hours, we’ve had 2,926 new confirmed cases of COVID-19 infections across the country,” health ministry spokesman Kianoush Jahanpour said in a televised news conference. “This brings the overall confirmed cases to at least 32,332,” he added, noting that 11,133 of those hospitalised so far have recovered. AFP Source: Daily Trust
BREAKING: 14 New Cases Of COVID-19 Confirmed In Nigeria

BREAKING: 14 New Cases Of COVID-19 Confirmed In Nigeria

Coronavirus, NEWS
Fourteen new cases of coronavirus (COVID-19) have been confirmed in Nigeria, bringing the total number of cases to 65. The Nigeria Centre for Disease Control (NCDC) announced this in a tweet on Thursday night. A breakdown of the number of the additional cases showed that 12 new cases were discovered in Lagos while the remaining two were confirmed in the Federal Capital Territory (FCT). Six of the cases were detected on a vessel and three others were returning travellers into the country while the remaining case was a close contact of a confirmed case. On the other hand, the NCDC revealed that another case had been discharged, bringing the number of persons who have recovered from the virus to three.
Amidst Covid-19 scare, mammoth crowd attend Bayelsa musician’s coronation

Amidst Covid-19 scare, mammoth crowd attend Bayelsa musician’s coronation

NEWS
Over 500 persons gathered at a popular hotel in Yenagoa to witness the coronation of Ijaw music maestro, Pereama Freetown, as the “Living King of Ijaw music” on Wednesday. This is despite the state government ban on large crowd gatherings so as to maintain social distancing as the coronavirus pandemic rages on. The event which held in the heartbeat of Yenagoa, the state capital, attracted the fans of Ijaw music from neighbouring Delta and Rivers states. It was gathered that several attempts by music stakeholders to persuade the organisers to call-off the event due to the outbreak of coronavirus pandemic was not successful. One of the organisers, told Daily Trust that Pereama insisted that he would be crowned King of Ijaw music on Wednesday, March 25, 2020 in Yenagoa, saying he do
Gold in high demand as coronavirus spreads

Gold in high demand as coronavirus spreads

NEWS
Gold, prized by investors in times of crisis as a safe haven, is experiencing surging demand in the face of the coronavirus outbreak — from both commodity traders and retail buyers. The precious metal had forged a seven-year peak on commodity markets this month as traders sought shelter from the COVID-19 pandemic and its destructive economic impact. The commodity has also rocketed as investors seek to guard against rising inflation — with many central banks injecting immense amounts of liquidity into the financial system to counter virus fallout. – ‘Phone has not stopped’ – “The phone has not stopped ringing” because “demand has exploded”, said Alessandro Soldati, boss of Gold Avenue, the online retail arm of Swiss refiner and ingots producer MKS PAMP Group. Over the last three weeks, as
NAFDAC Issues Warning on Life-Threatening Pharmaceutical Products

NAFDAC Issues Warning on Life-Threatening Pharmaceutical Products

NEWS
The National Agency for Food and Drug Administration and Control (NAFDAC) says that it has been notified that the United States Food and Drug Administration (FDA) has issued a fresh warning to consumers about the significant dangers of ‘Miracle Mineral Solution’ (MMS). Similarly, the agency said that it was also notified of a study that show that the vast majority of in-use make-up products such as beauty blenders, mascara and lip gloss are contaminated with potentially life-threatening superbugs. In two separate alerts number 001/2020 and 002/2020 issued by the agency and posted on its website mid-February, they explained that the warnings came due to a recent rise in reported health issues of serious and potential life-threatening effects following the use of the products. The products
Pharmamax Amlodipine, Lisinopril Gain  Market Share in Nigeria

Pharmamax Amlodipine, Lisinopril Gain Market Share in Nigeria

NEWS
The Management of KCH Group has announced a phenomenal preference of its anti-hypertensive medicines marketed under the brand names- Pharmamax Amlodipine and Pharmamax Lisinopril for the management and control of high blood pressure among patients in the country. ‘’In value and volume, Pharmamax Amlodipine and Lisinopril have maintained an incremental customer preference for a period covering more than six months over similar products across the country,’’ said Morgan Nwanguma, Manager, Corporate Communications and New Media at KCH Group in a press statement. He said that in the latest audit by his organization using testimonies from doctors, pharmacists, and patients who prescribe, dispense and make use of these medicine respectively as well as reports from sales representatives working
Ohuabunwa ‘breaks the ground’ for N2 Billion Pharmacy Tower project

Ohuabunwa ‘breaks the ground’ for N2 Billion Pharmacy Tower project

NEWS
It was an auspicious gathering of who is who in the pharmacy and pharmaceutical health world in Nigeria as the president of the Pharmaceutical Society of Nigeria (PSN) inaugurated the Pharmacy Tower Project in Lagos. A property situated on a highbrow side of the city – Churchgate Street, Victoria Island, was the venue of the event of the ground-breaking ceremony and debenture launch. The site was the scene of events that will remain historic in the annals of the body of pharmacists in Nigeria as anchored by the PSN. According to the PSN president, “it is the flag off (of) the construction of the Pharmacy Tower, an eight storey building that will house a national Drug & Poison Information, Emergency Response and Research Centre, which will serve as a major resource centre for t
COVID-19: Nigeria Records Five New Cases, Total Infections Now 51

COVID-19: Nigeria Records Five New Cases, Total Infections Now 51

Coronavirus, NEWS
Five new cases of the COVID-19 have been confirmed in Nigeria, bringing the total number of cases in the country to 51. According to the Nigeria Center for Disease Control (NCDC), two of the cases are in the FCT, two are in Lagos, while one is in Rivers State. The NCDC further explained that three of the infected persons are returning travellers into Nigeria while the other two are close contacts of a previously confirmed case. This comes as states across the country are scaling up efforts to combat the spread of the virus. Residents have been asked to stay at home, stricter restrictions have been placed on public gatherings and people including governors and top officials are being forced to self-isolate. Among tho...
Coronavirus and the Pharma Industry in Nigeria – CBN Rises to the Occasion

Coronavirus and the Pharma Industry in Nigeria – CBN Rises to the Occasion

Cover Stories, NEWS
According to experts the new coronavirus (SARS-CoV-2) is a new strain of the virus that has not been previously identified in humans. SARS-CoV-2 is the virus that is responsible for the coronavirus disease (COVID-19) that is also becoming a major scare to global economies. In this cover PharmaTimes Editor, MORGAN NWANGUMA and CHIGBU NWAOBIA, Senior Correspondant take a deeper look at government’s intervention concerning the viral disease, its effect on global economy, and specifically the Pharma industry particularly in Nigeria. The lessons therein according to economic watchers are proving to be a huge eye opener. A recent pronouncement by Food and Drug Administration linking COVID-19 outbreak to the shortage of a drug in the United States due to shortage of Active Pharmaceutical I
Nigeria coronavirus case increases to 46

Nigeria coronavirus case increases to 46

Coronavirus, Latest Health News, NEWS
Nigeria’s centre for disease control on Wednesday morning confirmed two new cases of the coronavirus in the country, bringing the total number to 46. The two cases are located in Lagos and Osun States. “Two new cases of #COVID19 have been confirmed in Nigeria: 1 in Lagos and 1 in Osun,” NCDC tweeted. “Both cases are returning travellers to Nigeria in the last 7 days” “As at 07:00 am 25th March, there are 46 confirmed cases of #COVID19 in Nigeria. 2 have been discharged with 1 death
Confirmed Cases of Coronavirus In Nigeria Rises To 44

Confirmed Cases of Coronavirus In Nigeria Rises To 44

Coronavirus, NEWS
Two new cases of the coronavirus disease have been confirmed in Nigeria, taking the total number of cases in the country to 44. The Nigeria Center for Disease Control (NCDC) announced this on Tuesday March 24, 2020. According to the NCDC, one of the cases was confirmed in the FCT, while the other is the governor of Bauchi State, Bala Mohammed. “The cases have travel history to Germany and the UK,” it added. Here’s a breakdown of the cases: Lagos- 29 FCT- 8 Ogun- 3 Ekiti- 1 Oyo- 1 Edo- 1 Bauchi-1.